Synthesis of [3H](4-fluorobutyl)propyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine: a potent radioligand for corticotropin-releasing hormone type 1 receptor

Dissecting the role of Corticotropin-releasing hormone receptor type 1 in Alzheimer's Disease

Pharmacopsychiatry ◽

10.1055/s-0031-1292513 ◽

2011 ◽

Vol 44 (06) ◽

Author(s):

K Lerche ◽

M Willem ◽

K Kleinknecht ◽

C Romberg ◽

U Konietzko ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Hormone Receptor ◽

Receptor Type ◽

Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice

Neuroscience ◽

10.1016/s0306-4522(01)00475-4 ◽

2002 ◽

Vol 109 (2) ◽

pp. 253-266 ◽

Cited By ~ 51

Author(s):

R.G Peñalva ◽

C Flachskamm ◽

S Zimmermann ◽

W Wurst ◽

F Holsboer ◽

...

Keyword(s):

Hormone Receptor ◽

In Vivo Microdialysis ◽

Mutant Mice ◽

Receptor Type ◽

Releasing Hormone ◽

Serotonergic Neurotransmission ◽

Microdialysis Study

Corticotropin-releasing hormone modulates airway vagal preganglionic neurons of Sprague–Dawley rats at multiple synaptic sites via activation of its type 1 receptors: Implications for stress-associated airway vagal excitation

Neuroscience ◽

10.1016/j.neuroscience.2017.04.049 ◽

2017 ◽

Vol 355 ◽

pp. 101-112 ◽

Cited By ~ 2

Author(s):

Yuhong Guo ◽

Xianxia Yan ◽

Xingxin Chen ◽

Ding He ◽

Ming Zeng ◽

...

Keyword(s):

Sprague Dawley ◽

Releasing Hormone ◽

Preganglionic Neurons ◽

Sprague Dawley Rats

Central Deficiency of Corticotropin-Releasing Hormone Receptor Type 1 (CRH-R1) Abolishes Effects of CRH on NREM But Not on REM Sleep in Mice

SLEEP ◽

10.1093/sleep/33.4.427 ◽

2010 ◽

Vol 33 (4) ◽

pp. 427-436 ◽

Cited By ~ 29

Author(s):

Christoph PN Romanowski ◽

Thomas Fenzl ◽

Cornelia Flachskamm ◽

Wolfgang Wurst ◽

Florian Holsboer ◽

...

Keyword(s):

Rem Sleep ◽

Hormone Receptor ◽

Receptor Type ◽

Divergent effects of corticotropin releasing hormone on endothelial cell nitric oxide synthase are associated with different expression of CRH type 1 and 2 receptors

British Journal of Pharmacology ◽

10.1038/sj.bjp.0704322 ◽

2001 ◽

Vol 134 (4) ◽

pp. 837-844 ◽

Cited By ~ 21

Author(s):

Giuseppina Cantarella ◽

Laurence Lempereur ◽

Gabriella Lombardo ◽

Andrea Chiarenza ◽

Carlo Pafumi ◽

...

Keyword(s):

Nitric Oxide ◽

Endothelial Cell ◽

Nitric Oxide Synthase ◽

Releasing Hormone ◽

Oxide Synthase

Synthesis, molecular modeling and biological activity of methyl and thiomethyl substituted pyrimidines as corticotropin releasing hormone type 1 antagonists

Organic & Biomolecular Chemistry ◽

10.1039/b305458f ◽

2003 ◽

Vol 1 (19) ◽

pp. 3353-3361 ◽

Cited By ~ 16

Author(s):

Adam McCluskey ◽

Paul A. Keller ◽

Jody Morgan ◽

James Garner

Keyword(s):

Biological Activity ◽

Molecular Modeling ◽

Letter to editor: Failure to replicate the association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants with risk of depression during pregnancy and post-partum reported by Engineer et al. (2013)

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2014.04.016 ◽

2014 ◽

Vol 56 ◽

pp. 168-170 ◽

Cited By ~ 11

Author(s):

Evie Stergiakouli ◽

Jonathan A.C. Sterne ◽

George Davey Smith

Keyword(s):

Hormone Receptors ◽

Post Partum ◽

Gene Variants ◽

Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

The Journal of Comparative Neurology ◽

10.1002/cne.23082 ◽

2012 ◽

Vol 520 (14) ◽

pp. 3150-3180 ◽

Cited By ~ 33

Author(s):

Claudia Kühne ◽

Oliver Puk ◽

Jochen Graw ◽

Martin Hrabě de Angelis ◽

Günther Schütz ◽

...

Keyword(s):

Hormone Receptor ◽

Receptor Type ◽

Chromaffin cell function and structure is impaired in corticotropin-releasing hormone receptor type 1-null mice

Molecular Psychiatry ◽

10.1038/sj.mp.4001143 ◽

2002 ◽

Vol 7 (9) ◽

pp. 967-974 ◽

Cited By ~ 22

Author(s):

M Yoshida-Hiroi ◽

M J Bradbury ◽

G Eisenhofer ◽

N Hiroi ◽

W W Vale ◽

...

Keyword(s):

Hormone Receptor ◽

Chromaffin Cell ◽

Cell Function ◽

Receptor Type ◽

The Role of the CRH Type 1 Receptor in Autonomic Responses to Corticotropin- Releasing Hormone in the Rat

Neuropsychopharmacology ◽

10.1016/s0893-133x(99)00126-8 ◽

2000 ◽

Vol 22 (4) ◽

pp. 388-399 ◽

Cited By ~ 67

Author(s):

M Nijsen

Keyword(s):

Releasing Hormone ◽

Autonomic Responses